NCT05682885

The Effectiveness of Lymphatic Bypass Supermicrosurgery

The Effectiveness of Lymphatic Bypass Supermicrosurgery for Primary Lymphedema Prevention After Breast Cancer Axillary Lymph Node Dissection: a Randomized Controlled Study

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (estimated)
• Sponsor: Dharmais National Cancer Center Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study evaluate the effectiveness of lymphatic bypass supermicrosurgery (LBS) and axillary lymph node dissection (ALND) compare to ALND alone to prevent breast cancer treatment-related lymphedema (BCRL).

Detailed description

In the intervention group, LBS was performed after ALND with the intima-to-intima coaptation using the supermicrosurgery technique. The anastomosis is done between the afferent lymphatic vessel to the recipient's vein, or if possible, from the afferent to the efferent lymphatic vessel. The upper extremity lymphedema (UEL) index and indocyanine green (ICG) lymphography are utilized to evaluate the development of lymphedema.

Conditions

• Breast Cancer Related Lymphedema
• Lymphedema Arm

Interventions

Type	Name	Description
PROCEDURE	Lymphatic Bypass Supermicrosurgery	Axillary Lymph Node Dissection with Lymphatic Bypass Supermicrosurgery

Timeline

• Start date: 2022-10-06
• Primary completion: 2027-10-31
• Completion: 2027-11-18
• First posted: 2023-01-12
• Last updated: 2025-01-22

Locations

1 site across 1 country: Indonesia