NCT05681507

Efficacy of TTMPB in Adult Cardiac Surgery

Efficacy of Transversus Thoracic Muscle Plane Block in Adult Cardiac Surgery: A Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (estimated)
• Sponsor: Eric Albrecht · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare the efficacy of Transversus Thoracic Muscle Plane Block (TTMPB) integrated in a modern multimodal analgesia protocol, following the ERAS® recommendations, in adult patients undergoing planned open heart surgery. The main study question is: Does the addition of TTMPB to a standard analgesic protocol significantly improve analgesia following elective open heart surgery? The investigators will primarily compare postoperative opioid consumption and pain scores in patients who will be randomly allocated to one of two groups: The control group will receive standard analgesia per institutional Intensive Care Unit protocol. The intervention group will receive the same standard of care plus a TTMP block (40ml of bupivacaine 0.375%, total dose of 150 mg). The investigators will also study the impact of group allocation on secondary outcomes, such as the rate of early mobilization.

Conditions

• Acute Post Operative Pain

Interventions

Type	Name	Description
DRUG	Transversus thoracic muscle plane block	Ultrasound guided bilateral parasternal injection of bupivacain 0.375%, 20ml, at 4th thoracic vertebral level.
PROCEDURE	Standard postoperative analgesia	Standard of postoperative ICU analgesic care, per institutional protocol

Timeline

• Start date: 2022-12-01
• Primary completion: 2023-12-31
• Completion: 2024-05-31
• First posted: 2023-01-12
• Last updated: 2023-01-23

Locations

1 site across 1 country: Switzerland