NCT05678218

Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma

Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma - a Registration Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 245 (actual)
• Sponsor: Erasmus Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 110 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational cohort study is to assess the yield of preoperative endoscopic ultrasound focussed on lymph nodes in patients with presumed resectable perihilar (pCCA), intrahepatic (iCCA) or mid-common bile duct (CBD) cholangiocarcinoma. The main questions it aims to answer is: 1. The number of patients precluded from surgical work-up due to positive regional or extraregional lymph nodes identified by endoscopic ultrasound guided tissue acquisition 2. Characteristics during endoscopic ultrasound of lymph nodes associated with malignancy

Conditions

• Hilar Cholangiocarcinoma
• Intrahepatic Cholangiocarcinoma
• Common Bile Duct Neoplasms
• Cholangiocarcinoma
• Adenocarcinoma

Interventions

Type	Name	Description
PROCEDURE	Endoscopic Ultrasound registration	Registration of all findings during Endoscopic Ultrasound

Timeline

• Start date: 2022-09-05
• Primary completion: 2025-07-01
• Completion: 2025-08-01
• First posted: 2023-01-10
• Last updated: 2025-08-08

Locations

7 sites across 2 countries: Belgium, Netherlands