NCT05678023

Study About Contrast Media

Multicentre Randomized Trial on the Timing and Effect of Contrast Media on Patients with Adhesive Small Bowel Obstruction

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: University of Tartu · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients hospitalized with adhesive small bowel obstruction (SBO) are randomized to 2 study groups at admission after signing an informed consent form. Water-soluble contrast media (CM) will be administered after 4 or after 24 hours of nasogastric- tube decompression.

Detailed description

Patients presenting with symptoms of small bowel obstruction (SBO) will be evaluated and if the diagnosis of adhesive small bowel obstruction is made it must be decided what is the treatment of choice. If immediate surgery is needed- it will not be delayed If patients are eligible for conservative management- they will be randomized to 2 study groups- contrast media (CM) after 4 hours of nasogastric-tube decompression and after 24 hours of nasogastric-tube decompression. Contrast media challenge acquires radiographs (X-rays) to be taken after an interval (common practice) decided by the surgeon. If at any point patient needs surgery- it will not be delayed. The results are compared. The hypothesis is, that if CM is administered sooner- it will help SBO resolution

Conditions

• Small Bowel Obstruction

Interventions

Type	Name	Description
OTHER	Effect on contrast media depending on the time of its administratsion	CM is a common practice when it comes to the management of small bowel obstruction. However there is no consensus as when it should be administered

Timeline

• Start date: 2023-09-01
• Primary completion: 2025-03-30
• Completion: 2025-08-01
• First posted: 2023-01-10
• Last updated: 2025-03-30

Locations

1 site across 1 country: Estonia