NCT05677503

Determination of the Red Cell Distribution Width, NT-proBNP and cTnT in Acute Myocardial Infarction Patients

Determination of the Relationship Between Red Cell Distribution Width, NT-proBNP and cTnT in Acute Myocardial Infarction Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

Detailed description

Patients and methods: * Type of study: Observational prospective study * Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit. * Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients. * Study Methods: * A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge. 1. Full history: 1. Personal history: e.g. age, sex and smoking. 2. Family history of cardiac diseases 3. Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history 2. Detailed clinical examination 3. Electrocardiogram 4. Laboratory investigation: 1. Routine investigation in the form of CBC including RDW 2. Specific investigation which include NT-proBNP and cTnT

Conditions

• Myocardial Infarction

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	CBC	measurement of CBC will be performed at the time of admission and by the time of discharge
DIAGNOSTIC_TEST	(NT-proBNP)	measurement of serum NT-proBNP levels will be performed at the time of admission and by the time of discharge
DIAGNOSTIC_TEST	(cTnT)	measurement of cTnT levels will be performed at the time of admission and by the time of discharge

Timeline

• Start date: 2023-01-15
• Primary completion: 2023-06-30
• Completion: 2023-07-30
• First posted: 2023-01-10
• Last updated: 2023-01-12