NCT05674851

Modeling Organ Motion During Abdominal Imaging in Healthy Volunteers

Study and Modeling of Organ Motion During Abdominal Imaging

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

In this study, we plan to systematically analyze the motion of organs and tissues in the abdomen, to understand the physical mechanisms of three-dimensional (3D) motion and interactions of abdominal organs and tissues. This work will allow us to learn how to mathematically model and predict abdominal organ motion.

Detailed description

Specifically, we plan to conduct this study in 3 steps, in an order of increasing complexity, starting with the (intra-fractional) respiratory only motion, then adding intra-fractional GI motility motion, and finally the inter-fractional anatomical variations (adding food intakes and fecal excretion). The research methods described will allow the study team to develop the ability to estimate the motion of both tumor target and critical organs given the patient's MRI, CBCT or x-ray fluoroscopy images on the day of radiation treatment.

Conditions

• Healthy Volunteers

Interventions

Type	Name	Description
OTHER	MRI	collection of MRI scans for mathematical model development

Timeline

• Start date: 2023-05-23
• Primary completion: 2023-06-27
• Completion: 2023-06-27
• First posted: 2023-01-09
• Last updated: 2025-01-06

Locations

1 site across 1 country: United States