NCT05672706

A Study of Pressure Waveform Analysis in Coronary Artery-II

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: National Taiwan University Hospital Hsin-Chu Branch · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to test the feasibility of intracoronary adenosine administration during coronary flow reserve(CFR) and index of microcirculatory resistance(IMR) assessment in a population with angina. The main questions it aims to answer are: * Repeatability of CFR and IMR assessment while hyperemia with intracoronary adenosine was administered. * Evaluate the correlation of the intrinsic signal of coronary waveform versus physiologic ischemia, while defined by fractional flow reserve(FFR) and CFR respectively. * The predictive value of FFR, CFR, and IMR on major adverse cardiovascular outcomes in 3 years Participants will undergo FFR, CFR, and IMR assessments in the catheterization laboratory of the National Taiwan University Hospital Hsin-Chu Branch, then clinical events follow up for 3 years.

Conditions

• Ischemic Heart Disease

Interventions

Type	Name	Description
PROCEDURE	CFR and IMR group	Participants will undergo repeat intracoronary adenosine administration during CFR and IMR measurement

Timeline

• Start date: 2023-01-04
• Primary completion: 2025-12-31
• Completion: 2027-12-31
• First posted: 2023-01-05
• Last updated: 2023-01-05

Locations

1 site across 1 country: Taiwan