NCT05672160

Overal Survival After TAVI According to Sarcopenia

CT Evaluated Sarcopenia Independently Predicts the Overal Survival After Transcatheter Aortic Valve Implantation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 930 (actual)
• Sponsor: Nemocnice AGEL Trinec-Podlesi a.s. · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to compare the overal survival after transcatheter aortic valve implantation (TAVI) according to sarcopenia status evaluated from preprocedural CT scans. The main question it aims to answer is: • Is CT evaluated sarcopenia an independent predictor of overal survival after TAVI?

Detailed description

The patients suffering from aortic valve stenosis, that are not eligible for cardiosurgery were indicated to miniinvasive transcatheter aortic valve implantation (TAVI). The follow up of 930 patients were done in time interval from 1 to 11 years. In every patient the preprocedural CT scans were done. From these CT scans the L3 cross sections will be used for sarcopenia evaluation. Then we will statisticaly evaluate the overal survival after TAVI procedure in the relation with sarcopenia status. We will answer the main question: Is CT evaluated sarcopenia an independent predictor of overal survival after TAVI?

Conditions

• Sarcopenia
• Aortic Valve Stenosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	CT evaluated sarcopenia	At L3 level of CT scan we will measure the area and density of muscles and fat tissue. We devided the patients to sarcopenia and non-sarcopenia groups according to these values.

Timeline

• Start date: 2022-01-01
• Primary completion: 2023-01-01
• Completion: 2023-01-02
• First posted: 2023-01-05
• Last updated: 2023-01-05

Locations

1 site across 1 country: Czechia