NCT05669443

Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy

Application of Individualized Positive End-expiratory Pressure Using Electrical Impedance Tomography (EIT) in Patients Undergoing Robot Assisted Laparoscopic Prostatectomy : a Randomized Controlled Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (estimated)
• Sponsor: Gangnam Severance Hospital · Academic / Other
• Sex: Male
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Steep trendelenburg posture or pneumoperitoneum for surgery causes ventilation problems during surgery, so finding a way to overcome is a challenging task for anesthesiologists. In this study, for patients undergoing robot assisted laparoscopic prostatectomy under general anesthesia, anesthesia is going to perform by applying conventional positive end-expiratory pressure (PEEP 5cmH2O) or individually determined positive end-expiratory pressure values for each patient using electrical impedance tomography. We plan to compare intraoperative ventilation through arterial blood gas analysis to find out the way to improve intraoperative ventilation.

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
DEVICE	conventional PEEP	Maintain positive end expiratory pressure at 5 cmH2O throughout the surgery.
DEVICE	optimized PEEP	Immediately after induction of anesthesia, the patient remains unapplied to PEEP. After pneumoperitoneum + Trendelenburg posture, an appropriate PEEP value is derived using electrical impedance tomography (airtom®). And then derived value ( = optimized PEEP value) is applied until the end of the operation.

Timeline

• Start date: 2023-04-03
• Primary completion: 2024-11-10
• Completion: 2024-11-10
• First posted: 2022-12-30
• Last updated: 2024-04-08

Locations

1 site across 1 country: South Korea