NCT05667961

Predictors of Functional Remission in Discharged Patients With Schizophrenia After Long-term Drug Discontinuation

Predictors of Functional Remission in Discharged Patients With Schizophrenia After Long-term Drug Discontinuation: a Case-control Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 480 (actual)
• Sponsor: Shanghai Mental Health Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Study objectives: 1. Describe the characteristics of discharged patients with schizophrenia achieving functional remission after drug discontinuation. 2. Establish a prediction model of patients with schizophrenia having good prognosis after drug discontinuation.

Detailed description

There are 2 clinically important and urgent questions to be explored in this study: 1. Who is more likely to benefit from guided drug reduction or discontinuation? How to design an individualized treatment plan which can balance the risk of relapse and side-effects from antipsychotics? 2. What are the predictors of functional remission in patients with schizophrenia after drug discontinuation? This will be the first related study to be conducted in China.

Conditions

• Schizophrenia

Timeline

• Start date: 2022-09-15
• Primary completion: 2025-01-31
• Completion: 2025-03-31
• First posted: 2022-12-29
• Last updated: 2025-04-25

Locations

1 site across 1 country: China