NCT05666362

Hemodynamic Response to Pain During Retinopathy Of Prematurity Screening

Hemodynamic Response Of Premature Brain To Pain During Retinopathy Of Prematurity Screening: A Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 68 (actual)
• Sponsor: Alexandria University · Academic / Other
• Sex: All
• Age: 4 Weeks – 12 Weeks
• Healthy volunteers: Not accepted

Summary

Study of cerebral hemodynamic changes in preterm infant and the effect of topical anesthetic eye drops ( benoxinate hydrochloride 0.4% ) on PIPP score and cerebral hemodynamic changes during fundus examination in neonates with gestational age ≤ 34 weeks or birth weight ≤ 2.000 Kg regardless their gestational age , after postnatal day 28.

Conditions

• Preterm

Interventions

Type	Name	Description
DRUG	benoxinate hydrochloride 0.4% group	They will receive benoxinate hydrochloride 0.4% immediately before fundus
DRUG	saline 0.9% .	They will receive saline 0.9% before fundus examination in each eye .

Timeline

• Start date: 2023-01-20
• Primary completion: 2024-12-20
• Completion: 2025-01-15
• First posted: 2022-12-27
• Last updated: 2025-02-05

Locations

1 site across 1 country: Egypt