NCT05666297

Screening of Cardiac Abnormalities in the First Trimester of Pregnancy by Volumetric Acquisition

Screening of Cardiac Abnormalities in the First Trimester of Pregnancy by Volumetric Acquisition: an International Multicenter Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 302 (estimated)
• Sponsor: University of Campania Luigi Vanvitelli · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Ultrasound is one of the most important tools in pregnancy both for its diagnostic capacity, but also because it is not invasive. For physiological pregnancy, the Italian guidelines provide for the execution of 3 ultrasounds: one in the first trimester (between 11 and 14 weeks), one in the second trimester (between 20 and 22 weeks) and one in the third (between 30 and 36 weeks). weeks). Screening for cardiac abnormalities is done during second trimester ultrasound, also called structural ultrasound. However, the development of three-dimensional (3D) sonography has represented a dramatic shift in obstetrics as it allows for the acquisition of a volume of data rather than conventional planar or 2D scans. This method has allowed considerable progress in the study of the fetus in the initial stages of development and has opened new windows in the knowledge of anatomical malformations at an early age. The possibility of detecting structural anomalies already during the first trimester of pregnancy allows, in fact, to provide the patient with additional time for counseling and for any genetic tests.

Conditions

• Pregnancy
• Ultrasound
• Fetal Conditions
• Cardiac Abnormalities

Timeline

• Start date: 2022-12-20
• Primary completion: 2023-02-15
• Completion: 2023-05-15
• First posted: 2022-12-27
• Last updated: 2022-12-27

Locations

1 site across 1 country: Italy