Trials / Unknown
UnknownNCT05666089
Effect of N-acetylcysteine Versus Calcium Hydroxide Used as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Levels of MMP -9 in Periapical Fluids in Patients With Necrotic Pulp
Effect of N-acetylcysteine Versus Calcium Hydroxide Used as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Levels of MMP -9 in Periapical Fluids in Patients With Necrotic Pulp: A Randomized Clinical Trial
- Status
- Unknown
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- Cairo University · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
To compare the effect of N-acetylcysteine versus calcium hydroxide as intra canal medication on: * Intensity of postoperative pain. * Bacterial load reduction. * levels of MMP -9 in Periapical Fluids.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | N-acetyl cysteine | intracanal medication of NAC with concentration 1 gm/ml in the form of a paste |
| DRUG | Calcium hydroxide | intracanal medication of calcium hydroxide paste (metapaste) |
Timeline
- Start date
- 2023-02-01
- Primary completion
- 2024-02-01
- Completion
- 2024-03-01
- First posted
- 2022-12-27
- Last updated
- 2022-12-27
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05666089. Inclusion in this directory is not an endorsement.