NCT05665010

Precise Stratification of Genetic Risk of Ovarian Function Impairment

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Tongji Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Aging is a common problem in human society at present. The fertility decline, perimenopausal symptoms and senile diseases caused by ovarian aging seriously affect women's own health, offspring's health, family and social stability, and endanger national population security. Accurate stratification of genetic risk of ovarian aging has practical significance. Early and accurate identification of high-risk groups of premature ovarian aging can help such women to start early protection of ovarian function, preserve fertility to a greater extent, improve fertility quality, and also be conducive to early prevention and treatment of other systemic diseases and prognosis.

Conditions

• Premature Ovarian Insufficiency
• Diminished Ovarian Reserve
• Early Menopause

Interventions

Type	Name	Description
OTHER	Genetic susceptibility	Genetic susceptibility increases the risk of ovarian injury

Timeline

• Start date: 2021-11-01
• Primary completion: 2023-10-31
• Completion: 2024-10-31
• First posted: 2022-12-27
• Last updated: 2022-12-27

Locations

18 sites across 1 country: China