Clinical Trials Directory

Trials / Completed

CompletedNCT05663957

eVusheld Assessment reaL wORld Effectiveness in the VA Health System

An Observational Study to Assess the Real-World Effectiveness of EVUSHELD™ (Tixagevimab/Cilgavimab) as Pre-exposure Prophylaxis Against COVID-19 Among EVUSHELD-eligible Populations Receiving Care in VA Health System in the United States

Status
Completed
Phase
Study type
Observational
Enrollment
5,814 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

An AstraZeneca-sponsored observational, electronic healthcare record (EHR)-embedded retrospective cohort study to assess the real-world effectiveness of EVUSHELD against SARS-CoV-2 infection, COVID-19-related hospitalization, and other COVID-19 related outcomes in the total EUA-eligible patient population in the Department of Veterans Affairs (VA) Health System.

Detailed description

This a Phase IV observational, secondary data study to assess the effectiveness of Evusheld in preventing COVID-19 infection and severe outcomes using the electronic medical records from the nationwide integrated health system. The study is designed as an AstraZeneca-sponsored observational, electronic healthcare record (EHR)-embedded retrospective cohort study to assess the real-world effectiveness of EVUSHELD against SARS-CoV-2 infection, COVID-19-related hospitalization, and other COVID-19 related outcomes in the total EUA-eligible patient population in the VA Health System.

Conditions

Interventions

TypeNameDescription
DRUGEvusheldEVUSHELD users

Timeline

Start date
2023-01-04
Primary completion
2023-09-01
Completion
2023-09-01
First posted
2022-12-23
Last updated
2024-09-03

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05663957. Inclusion in this directory is not an endorsement.