Clinical Trials Directory

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UnknownNCT05662774

Clinical Application of Quantitative Ultrasonographic Analysis in Early Kidney Injury

The Clinical Application of Ultrasound for Acute Kidney Injury During Sepsis - From Macroscopic to Microscopic Renal Perfusion Perspectives

Status
Unknown
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
Second Affiliated Hospital of Soochow University · Academic / Other
Sex
All
Age
19 Years – 90 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study was to quantify overall blood flow and renal cortical perfusion in patients with septic acute kidney injury (AKI) using ultrasound (US) Doppler and contrast-enhanced ultrasound (CEUS).

Detailed description

Kidney ultrasound is the most widely used imaging modality in initial AKI workup as it is widely available and free of complications. It is clinically feasible to use US Doppler and contrast-enhanced US (CEUS) to detect macroscopic and microscopic changes in renal blood flow, and also cardiac output alterations.The aim was to analyze changes in US Doppler and CEUS quantitative parameters in patients with septic AKI to explore perfusion within the renal parenchyma, and also measure global renal blood flow and cardiac output.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTUltrasound contrast agent (Sonovue)Patients are diagnosed by intravenous injection of ultrasound contrast on the first day of admission and information is collected by diagnostic ultrasound instruments

Timeline

Start date
2023-01-01
Primary completion
2024-11-30
Completion
2024-11-30
First posted
2022-12-22
Last updated
2022-12-22

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05662774. Inclusion in this directory is not an endorsement.