NCT05658081

Comparison of Two Stapled Antimesenteric Anastomosis for CD: a Randomized Control Trial Study

Stapled Antimesenteric Functional End-to-end Anastomosis (Kono-S) Versus Stapled Antimesenteric Isoperistaltic Side-to-side Anastomosis for the Postoperative Recurrence of Crohn's Disease: a Randomized Control Trial Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 236 (estimated)
• Sponsor: Jinling Hospital, China · Academic / Other
• Sex: All
• Age: 16 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The postoperative recurrence of Crohn's diseases (CD) remains high. Stapled anti-mesenteric functional end-to-end anastomosis was safe for CD patients. Its impact on the postoperative recurrence of CD was unknown. Whether it is superior than the conventional anastomosis (stapled antimesenteric isoperistaltic side-to-side anastomosis) needs explored. The trial aims to compare the different impacts of the two antimesenteric anastomosis configurations on the anastomotic recurrence following bowel resection.

Conditions

• Crohn Disease
• Recurrence

Interventions

Type	Name	Description
PROCEDURE	Kono-S group	patients in this arm will receive stapled Kono-S anastomosis after bowel resection
PROCEDURE	Side-to-side group	patients in this arm will receive stapled antimesenteric isoperistaltic side-to-side anastomosis after bowel resection

Timeline

• Start date: 2022-12-08
• Primary completion: 2024-12-01
• Completion: 2029-12-01
• First posted: 2022-12-20
• Last updated: 2022-12-20

Locations

1 site across 1 country: China