NCT05656638

Treatment of Grammatical Time Marking in Post-Stroke Aphasia

Treatment of Grammatical Time Marking in Post-Stroke Aphasia: a Study of French-Speaking Subjects With Chronic Fluent and Non-fluent Aphasia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: University of Neuchatel · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The study aims to assess an individual or self-administered computer therapy's effectiveness in grammatical time marking. The main objective is to examine whether the therapy improves grammatical time marking of inflected verbs treated on the sessions. We also explore whether the observed progress can be transferred to untrained items, more ecological contexts and if is maintained two and four weeks after the end of treatment. This therapy will be administered to six individuals with brain lesions after stroke. Four individuals will take part of the individual therapy and two individuals will take part of the self-administered computer therapy. The therapy will last one month, at the rate of three weekly sessions of approximately one hour.

Conditions

• Brain Injury, Vascular
• Aphasia
• Stroke

Interventions

Type	Name	Description
BEHAVIORAL	Speech and language therapy	The treatment focuses on grammatical time marking. The aim of the treatment is to train underlying grammatical time marking processes, which were identified as deficient during a preliminary evaluation. The intervention is composed of 4 steps inspired by models and hypotheses from the literature on the subject. Step 1: "temporal adverbial selection", subject must identify the tense encoded in sentences and select the correct adverbial among those proposed. Step 2: "selection of inflected verb forms", subject must identify the tense encoded in the sentence and select the correct verb form among those proposed. Step 3: "production of inflected verb forms", subject must identify the tense encoded in the sentence and produce inflected verbs. Step 4: "semantic narration", subject must describe scenes using verbs inflected according to the previously defined reference time.

Timeline

• Start date: 2022-12-30
• Primary completion: 2024-04-16
• Completion: 2024-04-16
• First posted: 2022-12-19
• Last updated: 2024-05-14

Locations

1 site across 1 country: Switzerland