NCT05652322

Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure

A Randomized Trial Comparing Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Patients Hospitalized for Decompensated Chronic Heart Failure

• Status: Withdrawn
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Jan Kochanowski University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical study is to compare treatment regimens of loop diuretics in patients with decompensated heart failure. The main aim is to answer if early change from intravenous to oral loop diuretics is safe and effective.

Conditions

• Heart Failure

Interventions

Type	Name	Description
DRUG	Furosemide Pill 150% equivalent iv dose	change from intravenous to oral furosemide
DRUG	Furosemide Pill 200% equivalent iv dose	change from intravenous to oral furosemide
DRUG	Furosemide Injection	change from intravenous to oral furosemide

Timeline

• Start date: 2022-12-07
• Primary completion: 2023-12-01
• Completion: 2024-03-01
• First posted: 2022-12-15
• Last updated: 2025-02-20

Locations

3 sites across 1 country: Poland