NCT05651399

Comparison in Frequency of Hypotension Between Remimazolam and Propofol in Hip Surgery

Comparison in Frequency of Hypotension During Sedation of Propofol and Remimazolam in Spinal Anesthesia in Hip Surgery Patients: a Randomized Controlled Clinical Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Asan Medical Center · Academic / Other
• Sex: All
• Age: 20 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the incidence of hypotension between remimazolam and propofol for intraoperative sedation in patients undergoing hip surgery with spinal anesthesia.

Conditions

• Remimazolam
• Propofol
• Orthopedic Procedures
• Sedatives
• Anesthesia, Spinal

Interventions

Type	Name	Description
DRUG	Remimazolam	Patients receive remimazolam at a rate of 1 mg/kg/hr. When a patient's MOAA/S reaches 3 or less, the rate of remomazolam is maintained at a rate between 0.3 mg/kr/hr and 1.0 mg/kg/hr until the end of surgery.
DRUG	Propofol	Patients are administered propofol with an effect-site concentration of 1.0 mcg/mL to 2.5 mcg/mL by target controlled infusion.

Timeline

• Start date: 2022-12-26
• Primary completion: 2023-06-14
• Completion: 2023-06-14
• First posted: 2022-12-15
• Last updated: 2025-02-26

Locations

1 site across 1 country: South Korea