NCT05650944

How Important Are Hematological Parameters in the Prognosis of Severe Covid-19 Patients?

Department of Infectious Disease and Clinical Microbiology

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 125 (actual)
• Sponsor: Hisar Intercontinental Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

It is aimed to reveal the treatment and prognostic values by evaluating the differences in hematological parameters and indices, especially in dead Covid-19 cases. Material Method: It is planned to retrospectively examine the hemogram parameters of 125 male, 44 female and 169 critical Covid-19 patients hospitalized between 01.03.2020 and 31.12.2021. Subjects were divided into 2 groups as deceased (77) and living (92) patients according to demographic data such as age and gender. Statistical evaluation: All analyzes were SPSS 25.0, Kolmogorov Smirnov test was used to determine distribution, median and interquartile range (Tukey's Hinges Percentile) were used to summarize variables. The differences between the Independent-Samples Mann Whitney U Test and the data of the patient groups and the optimal cut-off values, sensitivity and specificity values will be determined by ROC analysis. It will be considered statistically significant when the p value is below 0.05 (with the two-tailed test)

Detailed description

The aim of this study is to examine the effectiveness of routine laboratory complete blood count parameters and rates as diagnostic and prognostic criteria in severe COVID-19.

Conditions

• COVID-19

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Hemogram	Sysmex XN-1000 hematological analyzer

Timeline

• Start date: 2020-03-01
• Primary completion: 2021-12-31
• Completion: 2022-09-30
• First posted: 2022-12-14
• Last updated: 2022-12-14

Locations

1 site across 1 country: Turkey (Türkiye)