NCT05650853

Exploration of eJaculatory Anatomy Concept Study (EJAC Study)

Study of the Biomechanical Anatomy of Ejaculation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: Clinique Pasteur · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Ejaculatory dysfunctions (ED) are an important cause of postoperative dissatisfaction, which lead to a decrease in the intensity of orgasms in 50% of patients. ED is a cause for concern for almost a third of patients who need surgery. Surgical techniques have been developed to limit the occurrence of postoperative ED, but their results remain heterogeneous. There are very few studies on the biomechanical anatomy of ejaculation. Ejaculation is a complex phenomenon involving different structures and in particular the Veru Montanum. This is the key element in the emission of ejaculate within the prostatic urethra. In addition, there is a structure located in the resection zone of the prostate adenoma. It has therefore been suggested that its resection was a primary source of ED. A single observational study carried out in by Gil Vernet et al in 1994 evaluated on a single healthy 18-year-old volunteer the ejaculatory mechanism of expulsion using an endorectal probe recording the movements of the prostate, the bladder neck and of the proximal urethra during ejaculation. A contemporary study of the biomechanics of the ejaculatory expulsion phase could confirm and improve understanding of the involvement of anatomical structures. The results of our study aim to adapt surgical techniques aimed at limiting the risk of postoperative ED.

Conditions

• Ejaculatory Dysfunction

Interventions

Type	Name	Description
OTHER	Transrectal ultrasound	Examinations for observation of the pre, per and post-ejaculatory phases
OTHER	Urethroscopy	Examinations for observation of the pre, per and post-ejaculatory phases

Timeline

• Start date: 2022-12-12
• Primary completion: 2023-01-09
• Completion: 2023-01-09
• First posted: 2022-12-14
• Last updated: 2026-03-06

Locations

1 site across 1 country: France