Clinical Trials Directory

Trials / Unknown

UnknownNCT05647941

Neo-adjuvant Chemotherapy Evluation in Gastric Cancer Patients Based on Circulating Exosomal LncRNA-GC1

Non-invasive Response Assessment of Neo-adjuvant Chemotherapy in Gastric Cancer Patients Based on Circulating Exosomal LncRNA-GC1

Status
Unknown
Phase
Study type
Observational
Enrollment
700 (estimated)
Sponsor
Chinese PLA General Hospital · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The investigators hope that through the analysis and research to find determine whether lncRNA-GC1 could serve as a non-invasive biomarker for monitoring the neo-adjuvant chemotherapy response for personalized medicine for gastric cancer.

Detailed description

The LncRNA-GC1could noninvasively track dynamics of tumor burden and has been proposed as a real-time biomarker that can provide both predictive and prognostic values. But the value in monitoring the neo-adjuvant chemotherapy response is unclear. The investigators hope that through the analysis and research to find determine whether lncRNA-GC1 could serve as a monitoring biomarker for patients with gastric cancer receiving neo-adjuvant chemotherapy.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTDetection of levels of circulating EV-derived lncRNA-GC1For patients with gastric cancer receiving neo-adjuvant chemotherapy, the dynamic changes of EV-derived lncRNA-GC1 was detected to identify whether is can serve as a monitoring biomarker for treatment response.

Timeline

Start date
2018-01-01
Primary completion
2022-12-30
Completion
2022-12-30
First posted
2022-12-13
Last updated
2022-12-14

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05647941. Inclusion in this directory is not an endorsement.