NCT05645705

A Two-Week Study of Clinical Safety and Saliva Flow Quantification

Two-Week Clinical Safety and Saliva Flow Quantification

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 270 (actual)
• Sponsor: Johnson & Johnson Consumer Inc. (J&JCI) · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess the oral tissue tolerance (tissues within the mouth) for irritation caused by added ingredients in mouthwashes. This will be assessed based on oral tissue exams and adverse reactions.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Colgate Cavity Protection Toothpaste	Participants will use Colgate Cavity Protection Toothpaste for brushing teeth twice daily.
OTHER	LISTERINE Cool Mint Antiseptic Mouthwash	Participants will use 20 mL of LISTERINE Cool Mint Antiseptic Mouthwash for 30 seconds after brushing twice daily.
OTHER	Listerine Advanced Gum Alcohol	Participants will use 20 mL of Listerine Advanced Gum Alcohol Rinse for 30 seconds after brushing twice daily.
OTHER	Listerine Advanced Gum Zero	Participants will use 20 mL of Listerine Advanced Gum Zero Rinse for 30 seconds after brushing twice daily.
OTHER	LISTERINE ULTRACLEAN Tartar Control Antiseptic Mouthwash Cool Mint	Participants will use 20 mL of LISTERINE ULTRACLEAN Tartar Control Antiseptic Mouthwash Cool Mint Rinse for 30 seconds after brushing twice daily.

Timeline

• Start date: 2022-11-28
• Primary completion: 2022-12-16
• Completion: 2022-12-16
• First posted: 2022-12-09
• Last updated: 2023-10-10

Locations

1 site across 1 country: United States