NCT05644418

EIT During FCV in the Intensive Care Unit

Electrical Impedance Tomography During Flow Controlled Ventilation in the Intensive Care Unit

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Erasmus Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to study the effects of Flow Controlled Ventilation (FCV) following conventional mechanical ventilation (Pressure or Volume Controlled Ventilation) in postcardiac surgery ICU-patients to allow for future power calculations and to obtain experience with FCV. The main questions it aims to answer are: * What is the effect of FCV on the lung volume measured by Electrical Impedance Tomography (EIT)? * What is the effect of FCV on the minute volume? * What is the effect of FCV on the mechanical power and dissipated energy? Participants will be ventilated with PCV at baseline and then switched to FCV for 90 minutes while the lung volume, minute volume and mechanical power and dissipated energy levels are measured.

Conditions

• Post-cardiac Surgery

Interventions

Type	Name	Description
DEVICE	Flow Controlled Ventilation (FCV)	FCV is started with the same settings as PCV (PEEP, Ppeak, FiO2) and after 30 minutes FCV is optimized concerning the driving pressure and PEEP using the dynamic compliance. After a total of 60 minutes the flow is adjusted based on the arterial blood gas.

Timeline

• Start date: 2022-02-22
• Primary completion: 2023-05-09
• Completion: 2023-05-09
• First posted: 2022-12-09
• Last updated: 2024-01-12

Locations

1 site across 1 country: Netherlands