NCT05642923

Post-COVID-19 Chronic Fatigue Syndrome

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 528 (actual)
• Sponsor: ClinAmygate · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Fatigue is recognized as one of the most commonly presented long-term complaints in individuals previously infected with SARS-CoV-2.

Detailed description

It has become increasingly clear that infected patients have symptoms not only in the acute phase, but also after recovery from the initial infection. A recent meta-analysis including 4828 patients with post-COVID-19 showed that symptoms and post-acute sequelae of SARS-CoV-2 can persist weeks to months after the infection. These patients who reported persistent symptoms have been termed "long haulers" or described as having long COVID, post-acute COVID-19, persistent COVID-19 symptoms, post COVID-19 manifestations, long-term COVID-19 effects, post-acute sequelae of COVID-19 (PASC), or post-COVID-19 syndrome.

Conditions

• Post-COVID-19 Syndrome
• Post-COVID Syndrome

Interventions

Type	Name	Description
DRUG	Synthetic Vitamin B1	Synthetic Vitamin B1 400 mg per day

Timeline

• Start date: 2023-01-08
• Primary completion: 2024-06-01
• Completion: 2025-03-05
• First posted: 2022-12-08
• Last updated: 2025-03-10

Locations

1 site across 1 country: Egypt