NCT05640206

Effect of Injectable Platelet-rich Fibrin on Disc Displacement Without Reduction

Effect of Intra-articular Injection of Injectable Platelet-rich Fibrin on Disc Displacement Without Reduction

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Ege University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This randomized clinical study was conducted on patients with disc displacement without reduction. Patient was selected one of the two study groups: control group received only arthrocentesis or test group received arthrocentesis + injectable platelet-rich fibrin (i-PRF). As primary outcome variable, pain was recorded at preoperatively and at postoperatively 1, 2, 3, 6 and 12 months. Maximum mouth opening, lateral and protrusive movements were formed as secondary outcome variables.

Detailed description

This randomized clinical study was conducted on patients with disc displacement without reduction. Patient was selected one of the two study groups: control group received only arthrocentesis or test group received arthrocentesis + i-PRF. Arthrocentesis procedure was performed for all groups with two needle technique. For test group, intra-articular i-PRF was made. As a primary outcome variable, pain was recorded at preoperatively and at postoperatively 1, 2, 3, 6 and 12 months. Maximum mouth opening, lateral and protrusive movements were formed as secondary outcome variables.

Conditions

• Disc Disorder

Interventions

Type	Name	Description
PROCEDURE	i-PRF	Arthrocentesis performed with two-needle technique, and then injection of i-PRF intra-articularly
PROCEDURE	Arthrocentesis	Arthrocentesis performed with two-needle technique

Timeline

• Start date: 2019-10-01
• Primary completion: 2021-07-01
• Completion: 2021-07-01
• First posted: 2022-12-07
• Last updated: 2022-12-08

Locations

1 site across 1 country: Turkey (Türkiye)