NCT05638490

Study on Prenatal Diagnosis and Closed-loop Management System of Congenital Talipes Equinovarus

Congenital Talipes Equinovarus Prenatal Diagnosis and Closed Loop Management System Single Center Observational Prospective Study Clinical Study Protocol

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The study intends to establish a closed-loop management from prenatal to postnatal through prospective cohort, and comprehensively utilize ultrasound and MRI technology to establish a prenatal diagnosis and evaluation system for congenital talipes equinovarus. On the basis of existing genetic testing, further use of whole-exome sequencing and other genomic methods to explore possible pathogenic genes and loci, and clarify the pathogenic mechanism of congenital talipes equinovarus. Therefore, congenital talipes equinovarus can improve its diagnosis and treatment capacity, reduce the disability rate related to congenital talipes equinovarus, and prevent it well.

Conditions

• Prenatal Diagnosis and Closed-loop Management System of Congenital Talipes Equinovarus

Interventions

Type	Name	Description
OTHER	—	no intervention

Timeline

• Start date: 2022-08-03
• Primary completion: 2024-08-01
• Completion: 2025-12-01
• First posted: 2022-12-06
• Last updated: 2022-12-06

Locations

1 site across 1 country: China