NCT05637580

Pathological Tumor and Lymph Node Responses After Neoadjuvant Immunochemotherapy in Initially-unresectable NSCLC

Real-world Analysis of Pathological Tumor and Lymph Node Responses After Neoadjuvant Immunochemotherapy in Initially-unresectable Non-small Cell Lung Cancer

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 110 (actual)
• Sponsor: Guangdong Provincial People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a real-world study with the largest sample size investigating the pathological tumor and lymph node responses to neoadjuvant immunochemotherapy in non-small cell lung cancer to date. Patients with initially unresectable NSCLC underwent immunochemotherapy and response to treatment was assessed after every two treatment cycles. Clinicopathologic features of patients including epidemiological data, clinical manifestations, operation strategies, pathological findings, and prognostic information were recorded and evaluated.

Conditions

• Non Small Cell Lung Cancer
• Immunotherapy
• Chemotherapy
• Tumour, Residual

Interventions

Type	Name	Description
DRUG	Timing of drug administration	The effect of drug administration timing on tumor and lymph node responses was observed.

Timeline

• Start date: 2019-05-20
• Primary completion: 2022-07-01
• Completion: 2022-07-01
• First posted: 2022-12-05
• Last updated: 2022-12-05

Locations

1 site across 1 country: China