NCT05635812

Brain and Eye Markers of Facial Expression Recognition and Disorders Associated with Autistic Symptoms

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: Centre Hospitalier Universitaire Dijon · Academic / Other
• Sex: All
• Age: 7 Years – 50 Years
• Healthy volunteers: Accepted

Summary

In everyday life, it is necessary to adjust one's behavior and reactions in order to interact and communicate with others in an appropriate manner. This adaptation is done by taking into account the emotions of the people with whom we interact. This reading of emotions is done by using visible clues on the face, in particular by observing the eye area of the interlocutor. The aim of the study is to investigate how processes such as attention or memory influence emotion recognition, as well as (i) their alteration in the disease, and (ii) their link with the emergence of autistic and/or psychotic symptoms. We also want to study the implementation of compensatory strategies (used to compensate for difficulties in recognizing or perceiving emotions) and the link between the correct use of these strategies and the emergence of autistic and/or psychotic symptoms. The present project plans to include a total of 120 participants: 30 participants with ASD, 30 patients with a particular genetic deletion 22q11.2 and 60 control participants. After the inclusion visit, participation in the study will be divided into two half-days in order to perform a neuropsychological assessment, an EEG study and an oculometry study.

Conditions

• Brain Markers

Interventions

Type	Name	Description
OTHER	Neuropsychological assessment	neuropsychological assessment and clinical scales duration: 3 hours
OTHER	EEG experimentation	duration: 1 hour
OTHER	Oculometry experimentation	duration: 30 minutes

Timeline

• Start date: 2023-07-06
• Primary completion: 2026-07-01
• Completion: 2026-07-01
• First posted: 2022-12-02
• Last updated: 2024-10-04

Locations

1 site across 1 country: France