NCT05634005

Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,543 (actual)
• Sponsor: University of Utah · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Determine whether clinical decision support (best practice advisory) improves provider adherence to transfusion guidelines for all four major blood components (red blood cells, plasma, platelets, and cryoprecipitate) using a randomized study design to reduce risk of bias. Alerts will be visible to the experimental ordering provider group, while they will not be visible to the control. Both groups still have access to information about best practices: local clinical transfusion guidelines are available and education on blood transfusion best practices will continue regardless of randomization assignment.

Conditions

• Anemia
• Thrombocytopenia
• Coagulopathy, Mild
• Hypofibrinogenemia

Interventions

Type	Name	Description
BEHAVIORAL	Clinical Decision Support	In blood product order entry within the electronic health record, the ordering provider is required to select an indication for the blood product order. If the patient's laboratory values are not in line with the guideline indication selected, a clinical decision support alert will fire and be shown to the ordering provider. This alert will inform the provider that the order is outside institutional guidelines and the provider has the option to cancel the order (or bypass the order and select a reason for proceeding with the order).

Timeline

• Start date: 2023-02-01
• Primary completion: 2024-02-01
• Completion: 2024-02-01
• First posted: 2022-12-01
• Last updated: 2025-03-06

Locations

1 site across 1 country: United States