NCT05633511

Changes of Soft Tissue Grafting: A Randomized Study

Volumetric Changes of Soft Tissue Grafting. Comparison of Autologous PRF (Platelet-rich Fibrin ) & Autogenous CTG (Connective Tissue Grafts) . A Split-mouth Randomized Design

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Tufts University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To correct gum recession, patient's own tissue from the roof of the mouth is harvested and placed where there is root exposed. This is considered gold standard of treatment. Sometimes patient don't want to have second surgical site in their mouth and at the same time do not want to use alternative tissue from human or animal donor. Using patients' blood and preparing it as a membrane is the next best thing to correct gum recession.

Detailed description

Patients that are interested in having corrective surgery for recession due to esthetic concerns or sensitivity will be enrolled in the study. The treatment site will randomly receive the procedure assignment. Intraoral scanner will be utilized to establish pre-op volume and will be repeated at each follow up visit. Total of 12 visits and 5 year duration is anticipated for the study.

Conditions

• Gingival Recession

Interventions

Type	Name	Description
PROCEDURE	Split Mouth Design	PRF on one side of mouth and CTG on the other side of participant's mouth.

Timeline

• Start date: 2023-01-11
• Primary completion: 2035-12-30
• Completion: 2036-12-30
• First posted: 2022-12-01
• Last updated: 2025-04-23

Locations

1 site across 1 country: United States