NCT05631925

Comparison of Two Different Anesthesia Methods in IVF Procedure

Comparison of Two Different Anesthesia Methods During Oocyte Retrieval for in Vitro Fertilization

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 130 (actual)
• Sponsor: Acibadem University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

In this study; during the oocyte retrieval procedure, it was aimed to compare two different general anesthesia methods, in which propofol was administered as infusion according to the patient's Bispectral index system (BIS) value or in bolus doses according to the patient's clinic.The hypothesis of the study; during the oocyte retrieval process, when propofol is administered as an infusion and accompanied by BIS monitoring, adequate anesthesia level will be achieved with less amount of bolus doses according to the clinical condition of the patient.

Detailed description

130 patients over the age of 18, ASA I-II, who underwent oocyte retrieval for IVF treatment were included in the study. The patients divided into two groups. In induction, 2mg/kg fentanyl, 40mg lidocaine and 2mg/kg propofol administered to all patients. Patients in group 1; propofol added in bolus doses of 0.5mg/kg. Doses determined according to the clinical condition of the patient. Patients in group 2; propofol administered as 10mg/kg/hour infusion. The infusion dose adjusted so that the Bispectral index (BIS) is in the range of 40-60.

Conditions

• Oocyte Retrieval

Interventions

Type	Name	Description
DRUG	propofol bolus	Propofol will be added in bolus doses of 0.5mg/kg.
DRUG	propofol infusion	Propofol will be administered as 10mg/kg/hour infusion.

Timeline

• Start date: 2022-05-27
• Primary completion: 2022-08-17
• Completion: 2022-08-17
• First posted: 2022-11-30
• Last updated: 2022-12-07

Locations

1 site across 1 country: Turkey (Türkiye)