Clinical Trials Directory

Trials / Terminated

TerminatedNCT05629208

Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

A Randomized, Blinded, Placebo-Controlled, Phase 2a, Proof-of-Concept Study to Evaluate Efficacy, Safety, and Tolerability of GS-5718 in Participants With Cutaneous Lupus Erythematosus (CLE)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
20 (actual)
Sponsor
Gilead Sciences · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The goal of this clinical study is to test how edecesertib (formerly known as GS-5718) can be useful in treating Cutaneous Lupus Erythematosus (CLE) in participants with CLE. Information on what is happening in the body relating to CLE, how the body processes, is affected by and responds to the study drug, and any study drug side effects will also be collected in this study.

Conditions

Interventions

TypeNameDescription
DRUGEdecesertibTablets administered orally
DRUGEdecesertib PlaceboTablets administered orally

Timeline

Start date
2023-04-17
Primary completion
2025-12-17
Completion
2026-01-14
First posted
2022-11-29
Last updated
2026-02-17

Locations

17 sites across 3 countries: United States, Germany, Spain

Regulatory

Source: ClinicalTrials.gov record NCT05629208. Inclusion in this directory is not an endorsement.