NCT05629065

Pathways to Advance Targeted and Helpful Serious Illness Conversations (PATH-SIC)

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 800 (estimated)
• Sponsor: Dana-Farber Cancer Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to increase serious illness conversations (SICs) about patients goals and preferences regarding their healthcare between patients with cancer and their oncology clinicians and improved care provided near the end of life.

Detailed description

The objective of this study is to implement an intervention in a pragmatic randomized controlled trial that uses cancer treatment pathways data to identify patients appropriate for serious illness conversations (SICs) and applies "nudges" to patients and their oncology clinicians to increase SICs and improve end of life (EOL) outcomes. Identified participants and clinicians will be randomized into 1 or 4 groups. * Nudge to patient and clinician * Nudge to patient only * Nudge to clinician only * No nudge. The expected enrollment is approximately 800 participants.

Conditions

• Breast Cancer
• Gastrointestinal Cancer
• Gynecologic Cancer
• Thoracic Cancer
• Genitourinary Cancer

Interventions

Type	Name	Description
OTHER	Clinician Nudge Email	-Clinician "nudge" email encouraging discussion to initiate discussion on SIC at next visit
OTHER	Patient Nudge Letter and Share questionaire	Involves patient nudge consists of a letter and SHARE questionnaire \- patient nudge is a letter and a SHARE questionnaire encourages the participant to complete the SHARE questionnaire, which asks questions about the participants goals and preferences around cancer care, and discuss the questionnaire with their oncology clinician at the next visit.

Timeline

• Start date: 2022-11-28
• Primary completion: 2024-09-30
• Completion: 2028-06-01
• First posted: 2022-11-29
• Last updated: 2025-08-28

Locations

1 site across 1 country: United States