Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05627648

Phase 3 Study of KP-100LI in Subjects With Vocal Fold Scar

A Multicenter, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Confirmatory Study For Intracordal Administration Of KP-100LI In Patients With Vocal Fold Scar

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
62 (estimated)
Sponsor
Kringle Pharma, Inc. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to confirm the efficacy and safety of KP-100LI, a intracordal formulation containing recombinant human dHGF as the active pharmaceutical ingredient, for voice function improvement therapy in patients with vocal fold scar (including vocal fold sulcus).

Conditions

Interventions

TypeNameDescription
DRUGKP-100LIIntracordal injection, 20 mcg once per week, 3 weeks
DRUGPlaceboIntracordal injection, once per week, 3 weeks

Timeline

Start date
2022-12-01
Primary completion
2026-08-31
Completion
2027-02-28
First posted
2022-11-25
Last updated
2025-12-05

Locations

8 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT05627648. Inclusion in this directory is not an endorsement.