Clinical Trials Directory

Trials / Completed

CompletedNCT05621811

Different Doses of Naronapride vs. Placebo in Gastroparesis

Double-blind, Randomised, Placebo-controlled, Dose-finding Phase IIb Trial to Evaluate the Efficacy, Safety, and Tolerability of a 12-week-treatment With Naronapride in Adult Participants With at Least Moderate Idiopathic or Diabetic Gastroparesis

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
328 (actual)
Sponsor
Dr. Falk Pharma GmbH · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This is a double-blind, randomized, multicenter, placebo-controlled, comparative phase II dose-finding trial. The trial will be conducted with four treatment groups in the form of a parallel group comparison and will serve to compare oral treatment with daily doses of 10, 20, or 40 mg Naronapride vs. placebo for the treatment of patients with Gastroparesis.

Conditions

Interventions

TypeNameDescription
DRUGNaronaprideNaronapride is a 5HT-4 agonist
DRUGPlaceboPlacebo

Timeline

Start date
2023-01-03
Primary completion
2025-08-12
Completion
2025-09-04
First posted
2022-11-18
Last updated
2026-04-15

Locations

22 sites across 2 countries: United States, Belgium

Regulatory

Source: ClinicalTrials.gov record NCT05621811. Inclusion in this directory is not an endorsement.

Different Doses of Naronapride vs. Placebo in Gastroparesis (NCT05621811) · Clinical Trials Directory