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Active Not RecruitingNCT05621317

A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
90 (estimated)
Sponsor
Aravax Pty Ltd · Industry
Sex
All
Age
4 Years – 17 Years
Healthy volunteers
Not accepted

Summary

The overall aims of this study are to demonstrate that treatment with PVX108 immunotherapy has an acceptable safety profile and is effective for reducing clinical reactivity to peanut protein in children and adolescents with peanut allergy.

Conditions

Interventions

TypeNameDescription
BIOLOGICALPVX-108PVX108 comprises a mixture of peptides that represent sequences from peanut allergens
BIOLOGICALPlaceboMatching placebo comprises the formulation vehicle without peptides

Timeline

Start date
2023-02-09
Primary completion
2025-11-01
Completion
2027-06-01
First posted
2022-11-18
Last updated
2025-10-15

Locations

14 sites across 2 countries: United States, Australia

Regulatory

Source: ClinicalTrials.gov record NCT05621317. Inclusion in this directory is not an endorsement.

A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy (NCT05621317) · Clinical Trials Directory