NCT05620641

Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy

Comparative Clinical Study Among Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to compare the possible efficacy of ondansetron and gabapentin on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.

Detailed description

This study will be a double blind randomized, controlled, parallel, study. A total of1 00 morbidly obese patients who will be scheduled for sleeve gastrectomy will be included in the study. The patients will be selected from those attending Gastrointestinal and Laparoscopic Surgery Unit, General Surgery Department, Tanta University Hospital, Tanta, Egypt. The participants will be randomized into two groups by closed envelop method,

Conditions

• Post Operative Nausea and Vomiting
• Sleeve Gastrectomy
• Morbid Obesity

Interventions

Type	Name	Description
DRUG	Ondansetron 8mg	50 patients will receive intravenous ondansetron 8 mg before the end of surgery.
DRUG	Gabapentin	50 patients will receive 600 mg oral gabapentin 1 h before anesthesia.

Timeline

• Start date: 2022-10-01
• Primary completion: 2025-02-28
• Completion: 2025-04-01
• First posted: 2022-11-17
• Last updated: 2025-04-17

Locations

1 site across 1 country: Egypt