NCT05618418

BActeriophages To Treat Liver Disease Eliminating Harmful Bacteria (BATTLE)

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Copenhagen University Hospital, Hvidovre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Alcoholic hepatitis is a disease with a high mortality rate with few treatment options improving survival. Recently certain bacterial strains has been correlated to survival in patients with alcoholic hepatitis. In the BATTLE-trial the investigators will investigate if certain bacteria are correlated to decreased chance of survival in patients with alcoholic hepatitis.

Detailed description

Patients with alcoholic hepatitis who are admitted to Copenhagen University Hospital Hvidovre and Herlev will be invited to participate. Blood and fecal samples following hospital admission will be collected. Through one-year follow-up correlation of certain bacteria in fecal samples with survival will be investigated. In particular whether patients with cytolysin producing E. faecalis has a decreased chance of survival compared to patients without this bacteria.

Conditions

• Alcoholic Hepatitis

Interventions

Type	Name	Description
OTHER	No intervention	No intervention

Timeline

• Start date: 2022-07-01
• Primary completion: 2025-01-01
• Completion: 2026-01-01
• First posted: 2022-11-16
• Last updated: 2022-11-16

Locations

1 site across 1 country: Denmark