Trials / Completed
CompletedNCT05615805
The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections
The Effect of Ocular Rinse Volume on Surface Irritation After Povidone-iodine Preparation for Intravitreal Injections: A Randomized Controlled Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 142 (actual)
- Sponsor
- University of Oklahoma · Academic / Other
- Sex
- All
- Age
- 18 Years – 100 Years
- Healthy volunteers
- Accepted
Summary
This is the first randomized controlled trial looking into post-injection rinse volume of standard ophthalmic eyewash and its affect on patient comfort up to 72 hours after injections.
Detailed description
Purpose To evaluate whether the volume of wash out rinse after povidone iodine (PI) application for intravitreal injections (IVI) affects patients' ocular surface irritation. Methods This was a prospective, single-masked, randomized-controlled trial consisting of 142 subjects . A total of 51, 45, and 46 patients received 3-mL, 10-mL, and 15-mL of ocular rinse respectively. Reductions in the Ocular Surface Disease Index (OSDI) and the Standardized Patient Evaluation of Eye Dryness II (SPEED II) surveys, conducted before and at 24-72 hours post-injection, were analyzed.
Conditions
- Intravitreal Injection
- Ocular Rinse
- Age-Related Macular Degeneration
- Diabetic Macular Edema
- Cystoid Macular Edema
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | OSDI questionnaire | Ocular Surface Disease Index |
| OTHER | SPEEDII questionnaire | Standardized Patient Evaluation of Eye Dryness II questionnaire |
Timeline
- Start date
- 2021-03-01
- Primary completion
- 2021-07-30
- Completion
- 2021-10-01
- First posted
- 2022-11-14
- Last updated
- 2023-04-25
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05615805. Inclusion in this directory is not an endorsement.