NCT05615779

Personalized B-fructan Diet in Inflammatory Bowel Disease Patients

The Fibre Study: RCT of Personalized Fibre Diet in IBD

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 600 (estimated)
• Sponsor: University of Manitoba · Academic / Other
• Sex: All
• Age: 6 Years – 39 Years
• Healthy volunteers: Accepted

Summary

This study aims to examine patient tolerability of personalized dietary fibre consumption recommendations (high-pectin diet versus high-B-fructan diet based on personalized responses), provided by an IBD dietician, based on our novel translational research findings.

Conditions

• Inflammatory Bowel Diseases
• Ulcerative Colitis

Interventions

Type	Name	Description
OTHER	Placebo Comparator: Randomized pectin diet	UC and healthy control participants randomized to receive recommendations provided by a dietician increasing consumption of foods high in pectin
OTHER	Randomized B-fructan diet	UC and healthy control participants randomized to receive recommendations provided by a dietician increasing consumption of foods high in B-fructan
OTHER	Personalized pectin diet	UC and healthy control participants to receive recommendations provided by a dietician increasing consumption of foods high in pectin based on personal host (biopsy) and microbe (stool) response at baseline
OTHER	Personalized B-fructan diet	UC and healthy control participants to receive recommendations provided by a dietician increasing consumption of foods high in B-fructan based on personal host (biopsy) and microbe (stool) response at baseline

Timeline

• Start date: 2023-08-01
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2022-11-14
• Last updated: 2025-04-06

Locations

2 sites across 1 country: Canada