NCT05615441

Effect of Nociception Level Monitoring During Remimazolam-based Total Intravenous Anesthesia on Intraoperative Opioid Requirements and Postoperative Pain

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 58 (estimated)
• Sponsor: Yonsei University · Academic / Other
• Sex: All
• Age: 19 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

This study aims to investigate whether the use of nociception monitoring during general anesthesia with remimazolam-based total intravenous anesthesia has an effect on intraoperative opioid requirements and postoperative pain. This study is a randomized trial with a 50% probability of being assigned to either group. Randomization will be done by an anesthesiologist not involved in anesthesia or postoperative outcome assessment. Patients and the investigator in charge of postoperative outcomes assessment will be blinded to group allocation.

Conditions

• Adult Patients Aged 19-64, Scheduled for Elective Arthroscopic Knee Surgery

Interventions

Type	Name	Description
DEVICE	Analgesia Nociception Index monitor	Patients will receive remimazolam-based total intravenous general anesthesia with nociception monitoring with the ANI monitor
DEVICE	Standard monitoring	Patients will receive remimazolam-based total intravenous general anesthesia based on hemodynamic monitoring and without nociception monitoring

Timeline

• Start date: 2022-11-02
• Primary completion: 2024-11-01
• Completion: 2024-11-01
• First posted: 2022-11-14
• Last updated: 2022-11-14

Locations

1 site across 1 country: South Korea