NCT05612048

A Study of Tooth Erosion in People With Esophagogastric Cancer

Pilot Study of Dental Erosion as a Non-invasive Biomarker of Esophagogastric Cancer

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 174 (actual)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The researchers are doing this study to find out more about what may lead to the loss of tooth enamel (the thin outer covering of the tooth) and how often it happens in people with esophagogastric cancer, colorectal cancer, pancreatic cancer, breast cancer, head and neck cancer, or non-small cell lung cancer, or a healthy volunteer.

Conditions

• Esophagogastric Cancer

Interventions

Type	Name	Description
OTHER	Survey	This is a 15-item questionnaire. The questionnaire asks subjects to quantify, during a specified duration of time, the number of times they have consumed or completed a task (ex. alcohol intake, cigarette use, and teeth brushing frequency). Additionally, the questionnaire further asks subjects to quantify their GERD symptoms and risk factors prior to diagnosis. All study procedures will be completed in one visit as part of a standard-of-care clinic visit.
OTHER	Intra-oral camera	Intraoral pictures of molars and incisors in 13 key regions
OTHER	Optional Salvia sample	Cohort 1 only. Participant is responsible for collecting and bringing the salvia sample to clinic.

Timeline

• Start date: 2022-11-03
• Primary completion: 2027-11-01
• Completion: 2027-11-01
• First posted: 2022-11-10
• Last updated: 2026-03-23

Locations

1 site across 1 country: United States