NCT05610644

Impact of Time Restricted Feeding on Daily Protein Requirements

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: All
• Age: 50 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The investigators aim to assess 24-hour protein kinetics at two different levels of protein intake: 0.8 (RDA) and 1.6g/kg/day (2RDA) during a normal dietary (TRAD) and a time restricted feeding (TRF) pattern in older adults.

Detailed description

The investigators aim to assess 24-hour protein kinetics at two different levels of protein intake: 0.8 (RDA) and 1.6g/kg/day (2RDA) during a normal dietary (TRAD) and a time restricted feeding (TRF) pattern in older adults. Individuals in the TRF pattern will only consume food during a 6-hour eating period and fast for the remaining 18 hours. Individuals in the TRAD pattern will consume isocaloric and isonitrogenous (RDA or 2RDA) diet but consume an all-beef-breakfast. Participants will consume oral stable isotopes to measure muscle protein synthesis (MPS), whole-body muscle protein breakdown (MPB), and whole-body protein balance (WBPB). Appropriate muscle, blood samples, and urine will be collected throughout a 24-hour metabolic trial following a 2-day controlled diet.

Conditions

• Nutrition Disorders in Old Age

Interventions

Type	Name	Description
OTHER	isocaloric, isonitrogenous meals	Participants will eat prepared study meals for 3 days that have either the RDA of protein per day or twice the RDA of protein per day.

Timeline

• Start date: 2023-03-29
• Primary completion: 2024-10-03
• Completion: 2024-10-03
• First posted: 2022-11-09
• Last updated: 2024-12-20

Locations

1 site across 1 country: United States