Trials / Unknown
UnknownNCT05610046
The Impact of Passive Heat Treatment on Glycaemic Response During an Oral Glucose Tolerance Test in Diabetic Patients
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Maastricht University Medical Center · Academic / Other
- Sex
- All
- Age
- 50 Years
- Healthy volunteers
- Not accepted
Summary
Type 2 diabetes mellitus (T2DM) is a metabolic disease with a rapidly increasing incidence world-wide. The disease is characterizedby a decreased glucose tolerance as a result of insulin resistance, resulting in poor blood glycaemic control. Blood glucose loweringmedications are widely available, but their effect stagnates as T2DM progresses. New treatment regimens are required to combatthe disease. Although therapies such as physical exercise have been shown to induce beneficial effects on glycaemic control inT2DM patients, not all patients are able to perform exercise. Passive heating treatment (PHT) might be an alternative strategy toreduce insulin resistance, as it has been postulated to have comparable effects on the cardiovascular system as exercise. PHT hasbeen linked to numerous health benefits, including improved cardiovascular- and pulmonary function, pain alleviation and metabolichealth. In addition, long term use of PHT shows promising effects on glycaemic control in T2DM patients. However, the acute effectsof PHT on glucoregulation are yet to be determined. Therefore, in this study we will assess the acute impact of passive heat treatment on the post-prandial glycaemic response during an OGTT in T2DM patients
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Infrared sauna heating | Participants will sit in an infrared sauna at 60° Celsius (humidity not controlled in an infrared sauna) for a total of 40 minutes. |
| DEVICE | Sham sauna | Participants will sit in an inactive infrared sauna at room temperature (21° Celsius) for a total of 40 minutes. |
Timeline
- Start date
- 2023-01-26
- Primary completion
- 2023-04-14
- Completion
- 2023-12-31
- First posted
- 2022-11-08
- Last updated
- 2023-05-06
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT05610046. Inclusion in this directory is not an endorsement.