NCT05609604

Role of Transcranial Direct Current Stimulation in Appetite and Weight Control

Role of Trans-cranial Direct Current Stimulation in Appetite and Weight Control: A Prospective Randomized Study

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 4 (actual)
• Sponsor: University at Buffalo · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To study the effects of transcranial direct current stimulation (tDCS) on weight and appetite.

Detailed description

1. To compare weight loss over one month in active tDCS group with sham tDCS group. The investigator will measure weight of every participants at the beginning of the study and one month after the last session of tDCS 2. To compare change in insulin sensitivity over one month in active tDCS group with sham tDCS group. The investigator will measure fasting insulin and glucose level, and calculate homeostatic model assessment-insulin resistance (HOMA-IR) 3. To compare change in cognitive performance as a response to food over one month in active tDCS group with sham tDCS group. The investigator will evaluate performance in a computerized task that measures executive functions under the presence of food (working memory, inhibitory control and a combination of both). The investigator will assess changes in accuracy and speed in the task under active tDCS versus sham tDCS. 4. To compare change in post-prandial glucose excursion and average meal counts per day. The investigator will use continuous glucose monitor to record the frequency and amplitude of glucose excursion.

Conditions

• Weight Loss
• Appetite Loss

Interventions

Type	Name	Description
DEVICE	tDCS	Electric current will be delivered to the pre-frontal cortex for 30 minutes.
DEVICE	Shame- No current

Timeline

• Start date: 2017-01-01
• Primary completion: 2022-10-25
• Completion: 2022-10-25
• First posted: 2022-11-08
• Last updated: 2024-01-30
• Results posted: 2024-01-30

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study