NCT05609162

Treatments for Brain Metastases With Poor Prognostic Factors

Effects of Local and Systemic Treatments in Brain Metastases With Poor Prognostic Factors: Multicenter Retrospective Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to learn about treatments in brain metastases with poor prognostic factors. The main questions it aims to answer are: * What kind of local treatment provides a survival benefit for patients with poor prognostic factors? * What kind of systemic treatment provides a survival benefit for patients with poor prognostic factors? * Will the combination of local treatment and systemic treatment provide a survival benefit for patients with poor prognostic factors? Participants will be asked to provide personal information about their living status, symptoms, and disease control during the follow-up.

Conditions

• Brain Metastases

Interventions

Type	Name	Description
PROCEDURE	neurosurgical resection	neurosurgical resection, stereotactic radiosurgery (SRS), whole brain radiotherapy(WBRT), EGFR target drugs, Immune checkpoint inhibitors，cisplatin, temozolomide

Timeline

• Start date: 2022-12-15
• Primary completion: 2023-11-20
• Completion: 2024-11-20
• First posted: 2022-11-08
• Last updated: 2022-12-15

Locations

1 site across 1 country: China