Clinical Trials Directory

Trials / Terminated

TerminatedNCT05604170

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

A Phase 3, Open-label Study of Adjunctive Ganaxolone (GNX) Treatment in Children and Adults With Tuberous Sclerosis Complex (TSC)-Related Epilepsy (TrustTSC OLE)

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
117 (actual)
Sponsor
Marinus Pharmaceuticals · Industry
Sex
All
Age
1 Year – 65 Years
Healthy volunteers
Not accepted

Summary

This is a Phase 3, global, open-label extension (OLE) study of adjunctive GNX treatment in children and adults with TSC who previously participated in either Study 1042-TSC-3001 or Study 1042-TSC-2001

Conditions

Interventions

TypeNameDescription
DRUGGanaxoloneGNX will be administered.

Timeline

Start date
2022-05-16
Primary completion
2025-04-02
Completion
2025-04-02
First posted
2022-11-03
Last updated
2025-10-01
Results posted
2025-10-01

Locations

54 sites across 10 countries: United States, Australia, Canada, China, France, Germany, Israel, Italy, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT05604170. Inclusion in this directory is not an endorsement.

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy (NCT05604170) · Clinical Trials Directory