NCT05601609

Are Sporadic Colorectal Cancers in Young Distinct From Elderly?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,599 (actual)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: —

Summary

In this study, the investigators compared and evaluated the clinicopathological and oncological characteristics of sporadic colorectal cancer (CRC) in young adults without genetic mutations associated with hereditary CRC syndrome and sporadic CRC in elderly individuals.

Detailed description

The ambiguity in the findings among several previous studies might be because of the difference in the age of the study population, yCRC and eCRC. The family history of CRC and cancer due to Crohn's disease or ulcerative colitis were also not excluded in such previous studies. Most importantly, those studies did not rule out the risk of hereditary cancer through the genetic testing in yCRC. Since hereditary CRC accounts for approximately 34% of those under the age of 35 years, it is necessary to exclude it to accurately compare the clinicopathological characteristics of sporadic cancer developed in yCRC and eCRC.

Conditions

• Colorectal Neoplasms

Timeline

• Start date: 2020-11-11
• Primary completion: 2021-06-10
• Completion: 2022-08-02
• First posted: 2022-11-01
• Last updated: 2022-11-01

Locations

1 site across 1 country: South Korea